Chondrocytes: anatomy and function - Kenhub
2024年3月19日 · Anatomy, histology and definition of cartilage. Chondrocytes produce collagen and the extracellular matrix. They are found in the avascular tissue known as cartilage. The extracellular matrix that is produced by the chondrocytes is important in the maintenance of cartilaginous tissue.
Chondrocyte - Wikipedia
Chondrocytes (/ ˈkɒndrəsaɪt, - droʊ -/, [1] from Greek χόνδρος (chondros) 'cartilage' and κύτος (kytos) 'cell') are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.
Histology, Chondrocytes - StatPearls - NCBI Bookshelf
2023年4月17日 · Chondrocytes maintain the extracellular matrix (ECM) and produce the cartilage matrix. Surrounded by collagenous fibers, chondrocytes release substances to make cartilage strong yet flexible. In general, chondrocytes are found within intervertebral discs and in any form of articular cartilage (AC).
Chondrocyte - an overview | ScienceDirect Topics
Chondrocytes are highly specialized cells that differentiate from clusters of mesenchymal cells during skeletal embryogenesis. The chondrocyte synthesizes and secretes the components of the extracellular matrix, primarily proteoglycans and type II collagen.
The art of building bone: emerging role of chondrocyte-to …
2018年6月14日 · This review focuses on the emerging models of chondrocyte-to-osteoblast transdifferentiation and their implications for the treatment of skeletal diseases as well as the possible signaling ...
The Origin and Fate of Chondrocytes: Cell Plasticity in …
2023年10月14日 · Here, we discuss the origin of chondrocytes, their destiny, and their plasticity in relationship to bone growth, articulation, and formation of the trabeculae. We also consider these processes from a biological, clinical, and evolutionary perspective.
Molecular Processes in Chondrocyte Biology - PMC - National …
2020年6月11日 · The molecular aspects of chondrocyte proliferation, differentiation, and death and the pathogenesis of OA and RA are going to be revealed, but extensive investigations are still needed to establish a molecular basis and develop new therapies and drugs.
The Role of Chondrocyte Morphology and Volume in Controlling …
Chondrocyte volume and morphology profoundly influence the stability of the chondrocyte phenotype and it is important to understand their involvement in OA pathology, cartilage repair, and cartilage engineering.
Chondrocyte - an overview | ScienceDirect Topics
The chondrocyte is one of a number of well-defined cell types in developing bone. Chondrocytes are the constituent cells of cartilage, and through their function in endochondral ossification—the process by which most vertebrate bones are formed—play a central role in determining the rate of bone growth (Hunziker, 1994).
The chondrocyte: biology and clinical application - PubMed
Chondrocyte is a unique cell type in articular cartilage tissue and is essential for cartilage formation and functionality. It arises from mesenchymal stem cells (MSCs) and is regulated by a series of cytokine and transcription factor interactions, including …