Kinetochore - Wikipedia
A kinetochore (/ k ɪ ˈ n ɛ t ə k ɔːr /, /-ˈ n iː t ə k ɔːr /) is a disc-shaped protein structure associated with duplicated chromatids in eukaryotic cells where the spindle fibers attach during cell division to pull sister chromatids apart. [1]
What is a Kinetochore? - ThoughtCo
2020年1月29日 · A kinetochore is the patch of protein found on the centromere of each chromatid. It is where the chromatids are tightly connected. When it's time, at the appropriate phase of cell division, the kinetochore's ultimate goal is move chromosomes during mitosis and meiosis.
Difference Between Centromere and Kinetochore | Definition, …
2017年3月15日 · The main difference between centromere and kinetochore is that centromere is the region where the two sister chromatids are held together after the replication of chromosome where kinetochore is the protein complex on the chromosome where spindle fibers are attached during cell division.
The Kinetochore - PMC
The kinetochore is a fascinating molecular machine that plays a central role in the fundamental processes that are required for the recognition, connections, and force generation that underlie mitosis.
Higher-order protein assembly controls kinetochore formation
2024年1月2日 · In this Article, we investigate how human cells confine outer kinetochore recruitment to centromere-localized inner kinetochore assemblies using the emergent properties conferred by...
An updated view of the kinetochore architecture - Cell Press
2023年9月27日 · This review highlights new insights into kinetochore rigidity, plasticity, and clustering, which are key to understanding temporal and spatial regulatory mechanisms of chromosome segregation.
Dictionary - Cell: Kinetochore - The Human Protein Atlas
Kinetochores are large protein structures that form over the specialized centromeric chromatin regions of chromosomes and to which microtubules from the mitotic spindle attach in mitosis and meiosis.
A blueprint for kinetochores — new insights into the ... - Nature
2011年6月2日 · The kinetochore is a large complex of proteins that physically links centromeric DNA to microtubules. Recent research has identified the individual kinetochore building blocks and studied how...
Centromeres and Kinetochores - Cell Press
The kinetochore, the protein complex assembled at each centromere, serves as the attachment site for spindle microtubules and the site at which motors generate forces to power chromosome movement.
Kinetochore assembly throughout the cell cycle - PubMed
The kinetochore plays an essential role in facilitating chromosome segregation during cell division. This massive protein complex assembles onto the centromere of chromosomes and enables their attachment to spindle microtubules during mitosis.
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