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Ergotamine - Wikipedia
Ergotamine, sold under the brand name Ergomar among others, is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline. [9] It is structurally similar to several neurotransmitters, and it acts as a vasoconstrictor.
Ergotamine: Uses, Interactions, Mechanism of Action - DrugBank …
Ergotamine reduces extracranial blood flow, causes a decline in the amplitude of pulsation in the cranial arteries, and decreases hyperperfusion of the territory of the basilar artery. It does not reduce cerebral hemispheric blood flow. Mechanism of action.
Ergotamine - Drugs.com
2023年12月12日 · Ergotamine is an ergot alkaloid medicine that is used to treat a vascular headache (such as a migraine or cluster headache). Ergotamine is not for daily use. Do not use ergotamine for common tension headaches. Ergotamine may also be used for purposes not listed in this medication guide. Ergotamine side effects.
Ergotamine tartrate is mainly used for the treatment of migraine by relieving the symptoms. Because ergonovine has been discontinued, oxytocin and prostaglandin preparation are the mainstream at present. The combination of ergota-mine tartrate and caffeine can increase the absorption of ergotamine and enhance the contraction of blood vessels.
In one of the first efficacy studies on oral ergotamine, the drug, used in a dose of 2 mg/h up to a total of 8 mg, resulted in relief of headache in 41% and improve-ment in 27% of 56 patients (31). In contrast, 0.5 mg ergotamine i.v. resulted in freedom from headache in 89% and improvement in 5% of 140 patients.
The pharmacology of ergotamine and dihydroergotamine
The ergot alkaloids are a family of chemical entities that have many pharmacologic effects. Their diversity results from their interaction with multiple receptors, their variable receptor affinity and intrinsic activity, and their variable organ-specific receptor access.
Ergotamine Tartrate Sublingual: Uses, Side Effects ... - WebMD
This medication is used to treat or prevent a certain type of headache (vascular headaches such as migraine headaches and cluster headaches). Ergotamine helps narrow widened blood vessels in the...
Ergot Alkaloids: A Review on Therapeutic Applications
2016年5月9日 · PDF | research article on ergot alkaloids | Find, read and cite all the research you need on ResearchGate.
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