Why is methoxide a strong base? - Chemistry Stack Exchange
2013年6月23日 · Why is methoxide strong base? In case of halogens, I get why one is weak base, and one is strong base, but in the case of ones with oxygen, this seems to be hard to figure out. CHX3OX− C H X 3 O X −. Thanks for contributing an answer to Chemistry Stack Exchange! Not the answer you're looking for? Browse other questions tagged or .
Is methoxide a better nucleophile than hydroxide?
2015年8月14日 · Therefore hydroxide ion is slightly more nucleophilicity than methoxide ion. My answer would be same as the above mentioned. I would just add that of the reduction in nucleophilic character of methoxide due to steric factors is 10 then an increase due to inductive factor is 40 which makes a net +30 better than hydroxide.
Negative charge of methoxide anion - Chemistry Stack Exchange
2013年8月3日 · 1. Why is the methoxide (CHX3OX− C H X 3 O X −) anion negatively charged? It has 13 valence electrons and has 13 free electrons. In spite of that the methoxide anion is negatively charged. organic-chemistry. electronic-configuration. covalent …
ph - Which one of the two is the stronger base: methoxide ion or ...
2020年8月5日 · Therefore it destabilizes the methoxide ion. $\ce{-H}$ has a comparatively lesser +I. This leads to the conclusion that $\ce{OH-}$ is more acidic than $\ce{CH3O-}$. This seems like a valid argument, but the order varies in gaseous/aqueous phases, because we consider polarizabilty and solvation effect, rather than inductive effect there
organic chemistry - Reaction of NaOH with methanol and ethanol ...
2016年9月17日 · The reaction of methanol and ethanol are based on their pKa p K a values in the reaction. Fist consider the reaction of methanol with water along with their pKa p K a values. CHX3OHpKa=15.5 +NaOH CHX3OX−NaX+ + HX2OpKa=15.74 C H X 3 O H p K a = 15.5 + N a O H → C H X 3 O X − N a X + + H X 2 O p K a = 15.74. Now you can see that pKa p K a ...
organic chemistry - Reaction between chlorobenzene and sodium …
2016年9月4日 · The benzyne intermediate is very electrophilic and nucleophilic attack by methoxide ion proceeds rapidly to give anisole. Although this reaction is well-documented with both $\ce{NaOH}$ and $\ce{NaNH2}$, I can't find any real-life examples with $\ce{NaOMe}$. Most examples of chlorobenzene → anisole reactions involve some kind of catalyst.
Role of methanol in NaBH4 reduction - Chemistry Stack Exchange
2017年8月1日 · The resulting methoxide coordinates to X3 3 forming X3X− 3 X The electron donating character of the methoxy group makes the remaining protons more hydride which results in a more reactive hydride source. You need methanol to solve NaBH4, other solvents are not very suitable. The active reducing species can be NaBH4 or NaOCHxHx (in which NaBH4 ...
Synthesis of sodium methoxide - Chemistry Stack Exchange
2017年5月8日 · For synthesis of sodium methoxide, can we use sodium hydroxide in methanol and slow evaporation after dissolving sodium hydroxide? No, all that does is give you back your NaOH. Its not a strong enough base to completely deprotonate methanol. I use sodium metal in methanol, cooled in ice/water bath and stirred under nitrogen for safety.
When (R)-2-bromopentane reacts with sodium methoxide, what is …
I know that with a SN2 reaction mechanism this becomes (S)-2-methoxypentane, but with elimination this is trans-2-pentene. I know that elimination happens quickly when you apply heat. In this case we have a secondary alkyl halide so its possible to use SN2 or E2 due to methoxide being a strong nucleophile.
organic chemistry - Why is sodium methanethiolate still a better ...
2015年6月17日 · I'm looking at a problem where sodium methanethiolate and sodium methoxide, both in equal amounts, are being reacted with $\ce{CH3I}$ and the solvent is ethanol. I understand that sodium methanethiolate is a better nucleophile than sodium methoxide when the two are reacted in equal amounts with something like methyl iodide in a polar aprotic ...