These mice also exhibit a disrupted skin barrier, dysregulated microbiome, and upregulated JAK1/2 and STAT1 signaling caused by T cell- and NK cell-derived interferon (IFN)-γ. Four interventions in ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

NextPoint Therapeutics, a clinical-stage biotechnology company developing a new class of precision immuno-oncology and tumor-directed therapeutics targeting the novel B7-H7 axis, today announced an ...

The researchers found thousands of genes upregulated when the tardigrades were exposed to extreme radiation. Further analysis ...

Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, ...

Abnormalities in levels of microRNAs, affecting protein production, may tie to CTEPH development and progression; possible ...

THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...

A research team has established a virus-induced gene silencing (VIGS) system in taro, enabling researchers to rapidly verify ...

Idiopathic pulmonary fibrosis is a chronic, progressive, incurable lung disease, leading to irreversible lung tissue ...

In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has ...

This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

There is an imbalance in the gut flora of patients with epilepsy compared with healthy controls, according to a study published online.