About 100,000 Americans, mostly Black, have sickle cell disease, shortening lifespans, delaying puberty, damaging spleens and causing infections.

Gene and cell therapies bring fresh hope to people with genetic disorders, but recovery can be complex and long-term support remains sparse.

Stroke rates continue to rise among adults and children living with sickle cell disease, despite new standards of care meant to lower their risk, a new study finds. People with sickle cell are vulnerable to strokes caused by a blood vessel to the brain either bursting or becoming clogged,

For people with SCD, hemoglobin S (a mutated protein that transports oxygen) causes red blood cells to become curved (sickle-shaped) and stiff. This