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EurekAlert!
1 天
FOXM1 and PD-L1 in CDK4/6-MEK resistance in nerve tumors
A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, “Linking FOXM1 and PD-L1 to CDK4/6 ...
Armed robbery in Revesby
15 小时
FOXM1, PD-L1 Linked to CDK4/6-MEK Resistance in Nerve Tumors
We suggest that future therapeutic strategies targeting the oncogenic network of CDK4/6, MEK, PD-L1, and FOXM1 represent ...
News Medical
10 小时
The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance
A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Linking FOXM1 and PD-L1 to CDK4/6 ...
1 天
“抗癌神药”PD-1遭遇打击,FDA或将收窄适用范围
2021年,O药成为全球首个获批与化疗联合一线治疗晚期胃癌的PD-1抑制剂;2023年K药也获批这一适应症。然而在事后的检查中, FDA发现这些药物对于PD-L1阴性患者“似乎不太有利” ,所以才考虑给PD-1药物治疗胃癌增加限制条件。
Targeted Oncology
5 天
FDA ODAC Votes Against Checkpoint Inhibitors in PD–L1-Negative Esophageal Cancer
The FDA’s Oncologic Drug Advisory Committee voted against the use of checkpoint inhibitors in esophageal cancer with PD-L1 ...
FiercePharma
5 天
UPDATED: Experts support FDA's plan for restrictions on PD-1 drugs in stomach, esophageal ...
The days of broad stomach cancer labels for PD-1 inhibitors appear to be numbered. | The days of broad stomach cancer labels ...
Medpage Today on MSN
5 天
No Benefit for PD-1 Inhibitors in Certain Gastroesophageal Cancers, FDA Panel Says
The Oncologic Drugs Advisory Committee (ODAC) decided 10-2 with one abstention that PD-1 inhibitors do not have a favorable ...
Targeted Oncology
5 天
FDA ODAC Finds Limited Benefit for Checkpoint Inhibitors in Low PD-L1 Gastric Cancer
The FDA’s Oncologic Drug Advisory Committee voted against the use of checkpoint inhibitors in first-line advanced gastric ...
腾讯网
2 天
吴一龙教授:DCR 超 90%!PD-L1 x VEGF 双抗治疗 EGFR-TKI 耐药患者疗效及 ...
在这项探索 PM8002/BNT327 联合化疗在 EGFR 突变非小细胞肺癌患者的安全性和有效性的 II 期研究中,研究者入组了接受 EGFR-TKI 治疗后出现疾病进展的 EGFR 突变 NSCLC。这些患者接受 PM8002/BNT327 ...
FiercePharma
7 天
Ahead of adcomm, FDA challenges broad use of PD-1 drugs in stomach cancer patients
Besides stomach cancer, the FDA also raised a similar concern for PD-1 drugs in first-line esophageal squamous cell carcinoma ...
1 天
FDA或收窄PD-1适应证 中国会跟进吗
中国临床肿瘤学会 胃癌 ...
BioWorld
5 天
Discovery of PD-L1-degrading PROTACs with promising antitumor efficacy
A new series of proteolytic targeting chimeras (PROTACs) was designed by Zhejiang University of Technology scientists based ...
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