The neuraxial delivery of drugs has become a cornerstone in the management of pain, leveraging the pivotal roles of the dorsal root ganglion (DRG) and dorsal horn. These spinal structures are key in ...

The following is a summary of “Application of the grading system for “nociplastic pain” in chronic primary and chronic ...

The following is a summary of “Retrospective Evaluation of Bipolar Peripheral Nerve Stimulation for Nociceptive and Neuropathic Pain: A Pilot Study,” published in the September 2024 issue of Pain by ...

Blood samples and organs (stomach, liver, and kidneys) were collected for AST/ALT level determination and H&E staining, respectively. The anti-nociceptive effect of CL-P2 and CL-P2A (0.1, 1, or 10 ...

Nociceptive pain in response to peripheral noxious stimuli, and inflammatory pain resulting from tissue damage, serve as warnings that normal bodily function cannot resume until the stimulus ...

Box 1. Glossary. Aβ-fibers: large-myelinated nerve afferents or pathways that convey non-nociceptive input (e.g., tactile sensation) Aδ-fibers: small-myelinated nerve afferents or pathways ...