The researchers employed Synechocystis sp. PCC 6803, a cyanobacterium model, and introduced genes coding for pyruvate ...

Figure 1: Interactions in the active site of AAD. It is disappointing that Westheimer's simple but elegant explanation for the decreased pK a of Lys115 is now recognized as incorrect. However ...

Continuing this research, the team devised a "more haste, less speed" strategy that supplements the two reactions performed ...

Evidence suggests it is an autoimmune disorder that develops when the immune system mistakenly attacks glutamic acid decarboxylase (GAD). This enzyme triggers the production of neurotransmitter ...

The FDA is set to decide on four promising therapies in the next two weeks, including a CAR T for acute lymphoblastic ...

The researchers employed Synechocystis sp. PCC 6803, a cyanobacterium model, and introduced genes coding for pyruvate decarboxylase and alcohol dehydrogenase enzymes, essential in ethanol biosynthesis ...

Researchers from the TEDDY study highlight how specific genetic and environmental factors may drive early autoimmunity linked ...

Once full approval is granted Upstaza (eladocagene exuparvovec) will become the first disease-modifying treatment for AADC (aromatic L-amino acid decarboxylase) deficiency, as well as the first ...

In view of their unique mechanism of action, topical retinoids are prescribed widely in dermatology for both indicated purposes and several worthwhile, evidence-based off-label uses. For seasoned ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and ...

Researchers found that inhibition of ACMSD (aminocarboxymuconate semialdehyde decarboxylase), an enzyme restricted to liver and kidney, enhances de novo NAD + synthesis and significantly reduces ...

Continuing this research, the team devised a “more haste, less speed” strategy that supplements the two reactions performed by a single malate dehydrogenase decarboxylase with two different ...