This endothelial activation is associated with endothelial cell proliferation and plexiform lesion formation (Guignabert and Dorfmüller, 2017). Considerable progress has been made in the genomics of ...

Ferroptosis is an inflammatory mode of cell death that promotes complement activation and macrophage recruitment. In pulmonary arterial hypertension (PAH), pulmonary arterial endothelial cells exhibit ...

Pulmonary hypertension (PH) is a fatal progressive disease characterized by pulmonary endothelial injury and occlusive pulmonary vascular remodeling. Lysosomal protease cathepsin L degrades essential ...

When I was diagnosed with pulmonary hypertension (PH) at age 36, I was terrified. But then I remembered this wasn’t my first rodeo: I was born with sickle cell disease, and doctors said I wouldn ...

Because pulmonary arterial hypertension (PAH) often causes shortness of breath, swelling, and fatigue, exercise may seem like the last thing you should do. But the right kind -- with your doctor ...

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading ... Researchers Identify Over 2,000 Genetic Signals Linked to Blood ...

1 Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China 2 Department of Cardiology, Affiliated Hospital of Hebei University, Baoding, Hebei, China ...

Thirty-four relevant articles were identified. Twelve described immediate or short-term IOP elevation, and 22 described long-term or sustained IOP elevation. Pertinent details of these ...

The PubMed database was searched using combinations of the search terms, "glaucoma," "ocular hypertension," "pegaptanib," "bevacizumab," "ranibizumab," "aflibercept ...

A solitary pulmonary nodule (SPN) is an isolated lung growth surrounded by normal tissue. Most SPNs are benign (not cancerous) when they're diagnosed. However, some nodules can enlarge and change over ...

Challenges include potential unwanted effects, such as angiogenesis, and the risk of enhancing tumour growth and promoting pulmonary hypertension. Nevertheless, there is strong evidence that ...