Phase 1a results support further development of TX000045 (“TX45”) for Group 2 Pulmonary Hypertension in HFpEF (“PH-HFpEF”), based on favorable pharmacokinetic profile and impact on renal plasma flow ( ...

These mice also exhibit a disrupted skin barrier, dysregulated microbiome, and upregulated JAK1/2 and STAT1 signaling caused by T cell- and NK cell-derived interferon (IFN)-γ. Four interventions in ...

This study presents valuable insights into the organization of second-order circuits for gustatory neurons, particularly how they integrate opposing taste inputs and the metabolic states that regulate ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

Revolution Medicines, Inc. (NASDAQ: RVMD) Q3 2024 Earnings Call Transcript November 6, 2024 Revolution Medicines, Inc. misses on earnings expectations. Reported EPS is $-0.94 EPS, expectations were ...

New research from Scripps Research links Alzheimer’s disease and alcohol use disorder, showing similar gene expression ...

Patient enrollment in the Phase 1b hemodynamic trial remains ahead of expectation, with topline results now expected in late Q1’2025 or early ...

NextPoint Therapeutics, a clinical-stage biotechnology company developing a new class of precision immuno-oncology and tumor-directed therapeutics targeting the novel B7-H7 axis, today announced an ...

Differentially expressed circFKBP8(5S,6) is a circular RNA with coding potential identified in control volunteers and ...

The researchers found thousands of genes upregulated when the tardigrades were exposed to extreme radiation. Further analysis ...

Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, ...