Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...
This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona, a BIST Community centre, have created the first blueprint of the human spliceosome, the most complex and intricate molecular ...