The matchup: Two doses of psilocybin, the active ingredient in “magic mushrooms,” against a six-week course of the popular antidepressant escitalopram, often sold as Lexapro or Cipralex.

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A new study has estimated more than five million Americans could reap benefits if the Food and Drug Administration approved psilocybin as a treatment for depression. Psilocybin is a ...

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The psychedelic compound in magic mushrooms – psilocybin – can improve the symptoms of severe depression, according to the largest randomised, controlled trial of the therapy carried out to date.

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