They fight invaders, clear debris and tend neural connections, but sometimes microglia go rogue. Preventing this malfunction ...

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

However, two new studies looking at Microglia show promise for even more and potentially more effective treatments to combat ...

Low serum sodium concentrations in the blood are called hyponatremia, a prevalent clinical electrolyte disorder. In contrast ...

胶质母细胞瘤（GBM）被归类为四级胶质瘤，是中枢神经系统常见的内源性恶性肿瘤。尽管实施了包括较大限度手术切除、放疗和以替莫唑胺（TMZ）为基础的化疗联合后续序贯TMZ治疗的标准治疗方案，但新诊断的GBM患者的平均总生存（OS）时间仅为14.6个月。胶质母细胞瘤干细胞（GSCs）是一小部分具有自我更新和多向分化能力的GBM细胞，被认为是GBM肿瘤发生和发展的责任方。GSCs还具有辐射抵抗、化疗抵抗、 ...

Microglia are the brain’s immune cells playing an important role in maintaining neural function and responding to potential ...

Chronic hyponatremia is a condition in which blood sodium levels are low, leading to neurological and mental problems.

A strategy that simultaneously targets motor neurons, astrocytes, and microglia in ALS was found to extend survival in a ...

Optimizing iPSC differentiation significantly improves in vitro Alzheimer's disease models, leading to more accurate and ...

ioMicroglia are cryopreserved human iPSC-derived microglia powered by bit.bio’s opti-ox™ precision reprogramming technology, built so scientists no longer have to battle with long differentiation ...

Sun Y; Ma J; Li D; Li P; Zhou X; Li Y; He Z; Qin L; Liang L; Luo X BACKGROUND: Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system.