Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin ...

Endothelin (ET) is a recently discovered 21-amino acid peptide that has potent physiologic and pathophysiologic effects that appear to be involved in the development of heart failure. These ...

Article Google Scholar Edery P, Attié T, Amiel J, Pelet A, Eng C, Hofstra RMW, Bidaud C, Munnich A, Lyonnet S: Mutation of the endothelin-3 gene in the Waardenburg-Hirschsprung disease.

Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor ...

Adding Uptravi (selexipag) to standard-of-care PAH treatment within six months may reduce the risk of hospitalization, per a ...

To effectively adapt to change, living organisms rely on their ability to rapidly detect and process sensory information in ...

Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in ...

One type of drug used to treat PAH is endothelin receptor antagonists. ERAs, as they are called, help keep blood vessels from narrowing. But these drugs don’t work as well for Black patients as ...

Q3 2024 Earnings Call Transcript October 31, 2024 Travere Therapeutics, Inc. misses on earnings expectations. Reported EPS is ...

Vera Therapeutics has shown the effect of atacicept on kidney function in patients with immunoglobulin A nephropathy persists ...

Atrasentan previously demonstrated efficacy in the open-label AFFINITY basket trial, where it reduced the 24-hour urinary ...