(p)ppGpp, through its interaction with RNA polymerase, aids in managing replication conflicts and facilitates the loading of ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications ...

Keywords: DNA Damage; DNA Replication; Replication Stress; Genome Stability; Mutagenesis; Chemotherapy; Chemoresistance; Radioresistance; Targeted Therapy Important Note: All contributions to this ...

A large-scale study links the presence of these tiny molecules to increased aggressiveness in malignant tumors ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. The antibody-drug conjugate (ADC) puxitatug samrotecan ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

Summary: Researchers have discovered that the protein USP50 regulates DNA replication by managing which enzymes—nucleases or helicases—cleave or unwind DNA strands during replication. This control is ...

Finally, the researchers describe a way to exploit ecDNA’s high rate of replication and transcription: a conflict between DNA ...

The award will fund work on DNA replication and pathways for cancer treatment, and create a community lab for local students to get research experience.