(p)ppGpp, through its interaction with RNA polymerase, aids in managing replication conflicts and facilitates the loading of ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

A large-scale study links the presence of these tiny molecules to increased aggressiveness in malignant tumors ...

Finally, the researchers describe a way to exploit ecDNA’s high rate of replication and transcription: a conflict between DNA ...

The ability to genetically engineer plants is largely thanks to a microscopic helper: a bacterium called Agrobacterium ...

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

Tiny circles called ecDNA are critical in cancer development and drug resistance. An international team publishes landmark studies detailing new findings and potential therapies.

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles—until recently dismissed as ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Along with defending against pathogens, the body’s innate immune system helps to protect the stability of our genomes in ...

DNA catapults into spotlight. A trio of research papers from Stanford Medicine researchers and their international ...