PHILADELPHIA — The same technology that saved millions of lives during the COVID-19 pandemic appears to hold promise against another scourge of infectious disease, according to new research from the ...

They found that mRNA vaccines that target C. diff cells and the toxins they produce generated a lasting immune response in ...

Eubank, PharmD, BCIDP, Research Assistant Professor, University of Houston College of Pharmacy presented a scientific poster entitled: A phase 2, randomized double-blind study of ibezapolstat compared ...

promote germination of C. difficile spores and thereby increase the risk of recurrent CDI after successful treatment of an initial episode. On the other hand, secondary bile acids, which are ...

C. difficile is a bacterium that can cause infection with symptoms ranging from diarrhea to deadly colon damage. It spreads quickly via its hard-to-kill spores and commonly infects vulnerable ...

Clostridioides difficile, a spore-forming and anaerobic gram-positive bacterium, causes a wide-spectrum diarrheal disease that can ultimately lead to life-threatening conditions such as toxic ...

First, the preservation and restoration of beneficial bacterial classes in the gut provide resistance to recolonization by C. difficile. Second, these data, presented for the first time ...

In mice and in nonhuman primates, the experimental mRNA vaccine protected against first-time infections with C. difficile and also against relapsing infections, researchers reported in Science.

Today we report on a promising animal study of a mRNA vaccine that could one day prevent or treat infection with the dangerous, often hospital-acquired C. difficile bacteria. We also feature a ...