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中国科学院
28 天
中国科大发现编码p53蛋白突变促进肿瘤免疫逃逸机制
抑癌基因TP53(编码p53蛋白)通常发挥肿瘤监查的作用。TP53基因突变后转变为癌基因,是多种肿瘤发生发展的驱动因素之一。 中国科学技术大学生命科学与医学部免疫调节与免疫治疗重点实验室教授魏海明课题组发现,p53可以直接调控免疫细胞的发育、分化与 ...
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