Modified vaccinia Ankara immunization in nonhuman primate models of lethal mpox virus infection, although effective to some extent, has been linked to breakthrough lesions and throat swab viremia.
Pexa-Vec (pexastimogene devacirepvec) is a modified vaccinia virus that has been engineered to express immune-boosting cytokine GM-CSF. The PHOCUS trial of Pexa-Vec was terminated on the advice of ...
The Company's most advanced product candidate, Olvi-Vec (olvimulogene nanivacirepvec), is a proprietary, modified strain of the vaccinia virus. Olvi-Vec currently is being evaluated in ...
Protein vaccines are composed of purified or recombinant proteinaceous antigens from a pathogen, such as a bacterium or virus. When administered, a protective immune response is elicited against ...
myvac is a viral vector (MVA—Modified Vaccinia Ankara) based, individualized immunotherapy platform that has been developed by Transgene to target solid tumors. myvac-derived products are designed to ...