Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine ...

Naturally occurring peptide–nucleobase hybrids are rare. Here Pei et al. report the discovery and biosynthetic studies of the first peptide–nucleobase hybrid catalyzed by an RRE–YcaO ...

Scientists have discovered a method to create biohybrid molecules combining DNA and proteins using bacterial enzymes. This ...

Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...

Identification of potent COVID-19 main protease inhibitors by loading of favipiravir on Mg12O12 and Zn12O12 nanoclusters: an in silico strategy for COVID-19 treatment.

Daniel Neumark has developed novel spectroscopic and time-resolved experiments to investigate transition states, size-selected clusters, electron hydration in clusters and liquids, and ...

The granted patent US12042510B2 outlines a novel compound consisting of a modified oligonucleotide that is 15 to 30 nucleosides in length. This oligonucleotide features a nucleobase sequence that ...

The patent also describes the intended outcomes of the gene editing, such as inducing nucleobase alterations that could lead to frame shifts, premature stop codons, or aberrant transcripts in the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...