ITDD helps effectively manage chronic pain and spasticity in some patients but requires adherence to best practices and a ...

A frequency of 40 Hz, amplitude of 0.8 mm, and an acceleration of 4.9 m/s2 with a vertical type vibration was used. Results ...

Our study provides evidence of metabolic pathways upregulated during L. mexicana infection that may mediate anti-nociceptive effects experienced by CL patients and identifies macrophages as a source ...

The following is a summary of “Effect of limb position change on capsaicin-evoked pain: Evidence of interplays between the ...

In this article, we explore treatment options for fibromyalgia, what current research can tell us about the disease and what ...

The MRI scans offered the researchers data on a variety of pain signatures, including: the nociceptive-specific pain ...

Pain is an unpleasant sensory and emotional experience. Acute nociceptive pain is induced by noxious stimuli, and is often a result of an intense or potentially damaging stimulus. We used single ...

Chronic stress exacerbates neuropathic pain via the integration of stress-affect-related information with nociceptive information in the central nucleus of the amygdala. Pain. 2017;158(4):717-739.

Central sensitisation typically describes an increased responsiveness of nociceptive neurons in the central nervous system (CNS) to normal input. With central sensitisation, there are changes in the ...

Beyond ART26.12 in CIPN, Artelo's extensive library of small molecule inhibitors of FABPs has shown therapeutic promise for ...

Beyond ART26.12, Artelo’s extensive library of small molecule inhibitors of FABPs have shown therapeutic promise for the treatment of certain cancers, neuropathic and nociceptive pain, dermatologic ...

Correspondence to Dr Alex Scott, Department of Physical Therapy, University of British Columbia, Vancouver V6T 1Z4, Canada; ascott{at}mail.ubc.ca The authors of this paper, a group of international ...