“Don’t listen to all of these liars. The real reason that straight people walk so slowly is because they are not part of our agenda. You must walk fast when you are trying to take over the world… Be ...
This is a phenomenon referred to as heterozygote advantage. In some cases, a single allele can alter the physiological function of an individual in such a way as to make that person resistant to ...
Facial flushing in a 22-year-old ALDH2 heterozygote before (left) and after (right) drinking alcohol. The individual pictured in this figure has given written consent for publication of his ...
Admixture rates between Jews and non-Jews are high. Heterozygote testing programs have led to selective mating practices that are influencing allele frequencies. So, the genetics of Jewish ...
In this study, we investigated the neuronal activity of the dentate gyrus (DG) with electrophysiological and optical imaging tools during sleep-wake cycles. We found that the activity of major ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The evolving genetic landscape of inherited ...
Unpublished data from our group has shown glucosylated cholesterol is increased in GBA heterozygote neuronal cells and in the brain tissue of Parkinson’s disease patients. This indicates cholesterol ...
Correspondence to Dr Nozomu Kono, The University of Tokyo, Bunkyo-ku 113-0033, Japan; nozomu{at}mol.f.u-tokyo.ac.jp; Dr Stefano Romeo, Department of Clinical and Molecular Medicine, University of ...