Tramiprosate is a glycosaminoglycan mimetic designed to bind to Aβ peptides, thereby stopping the formation of amyloid plaques. Owing to the short duration (3 months) of the tramiprosate Phase II ...
A surprising finding by DiGabriele et al. 16 is that FGF-1 can bind heparin irrespective of the orientation of the glycosaminoglycan. In fact, as discussed below, the protomers within each FGF-1 ...
Lin Han obtained his BE degree from Tsinghua University in Beijing, P. R. China, and his PhD degree from the Massachusetts Institute of Technology in the area of Bio- and Polymeric Materials. After ...
Turns out sea cucumbers contain high levels of a chemical called fucosylated glycosaminoglycan in their skin, which people across Asia have been using to treat joint problems like arthritis for ...
The red module may be beneficial in aging via the preferential degranulation of mast cells; release of glucosamines, heparin (a glycosaminoglycan) and histamine, which induce vasodilatation ...
Recent research has uncovered a pivotal role for hyaluronic acid (aka hyaluronan, HA), a glycosaminoglycan found in the extracellular matrix of tissues like cartilage, in this immune modulation.
The Laboratory establishes cell lines from skin biopsies for enzyme studies. The Laboratory also provides enzyme and/or urine glycosaminoglycan studies for monitoring patients who have been treated ...
Thyroid autoimmune diseases like Graves disease are closely linked to thyroid eye disease and it is believed that antibodies directly affect the tissues of the orbit, leading to lymphocyte ...