1 Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China 2 Department of Cardiology, Affiliated Hospital of Hebei University, Baoding, Hebei, China ...
a vascular endothelial growth factor (VEGF) inhibitor, is widely used as a first-line treatment for metastatic colorectal cancer (mCRC), with hypertension being a common adverse effect. However, there ...
Hypertension: Occurred in 35% of patients, including Grade 3 hypertension in 18% of patients. Overall, 8% had their dose interrupted and 4.8% had their dose reduced for hypertension.
LaNova Medicines has advanced its PD-1xVEGF bispecific antibody to a first in-human trial in China after securing $42 million in a Series C1.
Ferroptosis is an inflammatory mode of cell death that promotes complement activation and macrophage recruitment. In pulmonary arterial hypertension (PAH), pulmonary arterial endothelial cells exhibit ...
The PubMed database was searched using combinations of the search terms, "glaucoma," "ocular hypertension," "pegaptanib," "bevacizumab," "ranibizumab," "aflibercept ...
Pulmonary hypertension (PH) is a fatal progressive disease characterized by pulmonary endothelial injury and occlusive pulmonary vascular remodeling. Lysosomal protease cathepsin L degrades essential ...
Thirty-four relevant articles were identified. Twelve described immediate or short-term IOP elevation, and 22 described long-term or sustained IOP elevation. Pertinent details of these ...