In normal human physiology, relaxin is upregulated during pregnancy where it exerts vasodilative effects, reduces systemic and pulmonary vascular resistance and increases cardiac output to accommodate ...

To address this issue, we generated novel human pericytes that carry a tissue inhibitor of metalloproteinase (TIMP)-3 transgene which can be upregulated following doxycycline addition. EC-pericyte ...

New research from Scripps Research links Alzheimer’s disease and alcohol use disorder, showing similar gene expression ...

Abnormalities in levels of microRNAs, affecting protein production, may tie to CTEPH development and progression; possible ...

Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune Encephalomyelitis - Medscape - Apr 01, 2009. 1 Department of ...

The researchers found thousands of genes upregulated when the tardigrades were exposed to extreme radiation. Further analysis ...

This study presents valuable insights into the organization of second-order circuits for gustatory neurons, particularly how they integrate opposing taste inputs and the metabolic states that regulate ...

This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

Harvard University researchers have identified the biological mechanism by which chronic stress impairs hair follicle stem ...