Diagram Of Trypanosoma Cell Trypanosoma brucei (gambiense). Cell structure. Labeled. Trypanosoma is a protozoan parasite. A simplified representation of the location of the major structural features ...

We apply a population genomics approach to examine this effect in an important human pathogen, Trypanosoma brucei gambiense. We determine that T.b. gambiense is evolving strictly asexually and is ...

which is caused by the fatal tropical disease Trypanosoma brucei rhodesiense. PaxMedica plans to file a new drug application for PAX-101 in Q4. The company also hopes to advance the product into ...

RNA editing pathway is a validated target in kinetoplastid parasites (Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp.) that cause severe diseases in humans and livestock. An essential large ...

Tse-tse flies transmit Trypanosoma brucei gambiense and T. b. rhodesiense that cause African trypanosomiasis in humans and Nagana in cattle and although cases have declined in recent years, infected ...

The first movie (on the left) shows serial tilted views of the 120 nm thick section from a cell of Trypanosoma brucei . Images were collected (TEM Tecnai F20) at one degree intervals over a range from ...

The lab is using a wide variety of cell-wide systems biology approaches to elucidate critical cellular processes in Trypanosomatid parasites that can be exploited for the development of drugs against ...

Understanding the molecular mechanisms that regulate intracellular iron homeostasis in Trypanosoma brucei, a “neglected” pathogen that causes African sleeping sickness in humans and nagana in cattle ...

These protists are obligatory parasites that include Trypanosoma cruzi (Chagas disease), Trypanosoma brucei spp. (sleeping sickness), and several Leishmania spp. The PFR is a unique and complex ...

Background The two Apolipoprotein L1 (APOL1) risk variants (RV), G1 and G2, are enriched in African populations due to resistance to Trypanosoma brucei, a parasite endemic in West Africa. This ...

Additional BLASTp searches showed that there is generally a single TbFUT1 gene homologue in each kinetoplastid species, and a phylogram of FUT sequences indicates that TbFUT1 homologues form a ...