The microglia, in turn, seem to benefit, revving up metabolism and phagocytosis. The liver protein ApoA-I was particularly good at bolstering the latter. Overall, the findings suggest that the brain’s ...

Researchers have developed an innovative CAR T-cell therapy to combat glioblastoma, the most common malignant brain tumor in ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

The alarm that they trigger starts a series of reactions inside the cells. When scavenger cells "sniff out" a bacterium, for ...

Many receptors are involved in this process, some with signalling capabilities, some without. Increasing evidence now shows a previously unappreciated regulatory component to phagocytosis exerted by ...

1 Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Japan 2 Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Japan For phagocytosis, ...

It features a wild-type IgG1 Fc structure and is currently in the clinical research stage. CD47 is overexpressed on a variety of cancer cells, where it interacts with its ligand SIRPα on innate immune ...

Researchers have developed a promising nasal spray therapy targeting neuroinflammation in Alzheimer’s disease, potentially ...

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

University of Pennsylvania, Philadelphia, PA.