葡萄糖饥饿诱导的CARM1表达上调提示其可能在胃癌细胞应对低糖应激中发挥重要作用。研究人员假设CARM1在低糖条件下促进细胞存活和增殖。在低糖条件下，敲低CARM1显著延迟了MGC-803和AGS细胞的增殖和克隆形成能力。流式细胞术分析显示，敲除CA ...

These experiments used the 4-octyl modification to ensure that itaconate could get into the cells. Itaconate’s anti-inflammatory action is thought to work by activating a signaling process in cells ...

This occurs through the Nrf2/ARE pathway, which is a crucial mechanism for combating oxidative stress within cells. The development of hepatocarcinogenesis is a multi-stage process that is ...

9月12日，安徽医科大学郭继政研究团队在期刊《Cell Death&Disease》上发表了研究论文，题为“The NRF2-CARM1 axis links glucose sensing to transcriptional and epigenetic regulation of the pentose phosphate pathway in gastric ...

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing ...

(C) Effects of 6-OHDA and sesaminol on nuclear translocation of Nrf2. SH-SY5Y cells were incubated with 1 μg/ml of sesaminol for 2 h, followed by treatment with 20 μM 6-OHDA for 3 h ...

通路分类基于癌症基因组图谱数据库预先定义的谱系（如RTK、RAS、RAF、MEK、NRF2、ER、WNT、MYC、P53、细胞周期、Notch、PI3K）[8]。ESR1和PIK3CA的单核苷酸 ...

Ecklonia cava, a type of brown algae seaweed, has demonstrated potential in protecting against neurodegenerative diseases.

Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway. Success rate of external, endonasal, and ...

The MSc Education (Open Pathway) allows you to design your own programme of study based on your areas of interest, rather than choosing one subject area from our specialist pathways. Units can be ...