New research shows that microglia, which usually clear debris, cause harmful inflammation in the presence of APOE4 protein.

CVN293 was generally well-tolerated in healthy participants with single doses up to 1000mg and multiple doses of up to 375mg twice daily for 14 days. No serious adverse events were reported and all ...

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for ...

By transplanting human neurons into the mouse brain and eliminating the mouse microglia, scientists at the Gladstone Institutes in San Francisco observed that amyloid and tau deposition was reduced.

Researchers find that a gene linked to Alzheimer's triggers inflammation in healthy brain immune cells, offering new insights ...

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

Researchers from the University of Colorado Anschutz Medical Campus have discovered how the common cold sore virus, HSV-1, ...

A team of scientists has found that the presence of the APOE4 protein -- the most important genetic risk factor for Alzheimer ...

A new therapy may delay Alzheimer's disease progression by years, according to a study by researchers at Texas A&M University ...

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system. Microglia, the primary immune cells of the central ...