Figure 1: Heparan sulfate proteoglycan is a receptor for AAV-2 virions. Identification of the AAV receptor and vector-specific reagents has led to the development of purification protocols for ...

Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.

To her disbelief, Sanfillipo Syndrome, had symptoms that her daughter had been experiencing, which she thought were just ...

We have speculated that HSV1 and apoEs might compete for entry into neuronal cells through heparan sulphate proteoglycan molecules (the initial site of attachment for entry for each), with apoE4 ...

Specifically, Sanfilippo makes the body unable to break down a molecule called heparan sulfate — a natural cellular substance usually metabolized and recycled through enzyme action. As a result ...

A new study published in the journal of Molecular Psychiatry found that heparin medication was linked to a delayed diagnosis ...

TD Cowen analyst Brendan Smith has maintained their bullish stance on DNLI stock, giving a Buy rating on November 1. Brendan Smith has given ...

Proteins that attach to HSPGs can build up in the brain for many years before symptoms appear, and a specific gene involved ...

Its biggest draw is its use of heparan sulfate, a sugar molecule that occurs naturally in the skin and is important for maintaining its health. “It promotes deep hydration, decreases ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

DNLI reports a wider-than-expected loss in the third quarter of 2024. Nonetheless, the pipeline progress has been encouraging.

Previous research demonstrated that the risk of developing Alzheimer’s may be linked to a protein called Apolipoprotein E (ApoE), which interacts with cell surface molecules known as heparan ...