In the trial, doses ranging from 0.5mg to 0.9mg of ALG-055009 led to notable median relative reductions in liver fat.

For the primary endpoint of AGV at Week 52, children treated with TransCon CNP (n=57) demonstrated an LS mean AGV of 5.89 ...

An NIH-supported clinical trial of pomalidomide in treating hereditary hemorrhagic telangiectasia stopped early due to ...

Patients with locally advanced cervical cancer were randomized to receive either pembrolizumab or placebo in combination with ...

METHODS A prospective, randomised, double blind placebo controlled trial. Patients received either nebulised budesonide or placebo every 12 hours. The main outcome measures were duration of inpatient ...

Objective: A randomised double-blind placebo controlled withdrawal clinical trial of prednisone versus placebo in patients with rheumatoid arthritis (RA), treated in usual clinical care with 1–4 ...

Here, we report the preventive effect of naldemedine versus placebo for constipation in patients with cancer starting an opioid therapy in a multicenter, double-blinded, randomized trial. We ...

Design: Double blind, randomised, placebo controlled trial. Setting: Community based rheumatology practice in Australia. Participants: 50 participants (24 active, 26 placebo); 46 completed the 12 week ...

Methods: We conducted a pediatric substudy as part of a double-blind, randomized, multinational trial to compare micafungin (2 mg/kg) with liposomal amphotericin B (3 mg/kg) as first-line ...

Three months of supplementation with a prebiotic blend of inulin and oligofructose may significantly improve measures of ...

Placebo-controlled trials have proven that topical budesonide suspension is effective for short-term treatment of EoE, achieving high histological remission rates. There is no oesophageal-targeted, ...

Neurocrine Biosciences has reported that its Phase II ERUDITE clinical trial of luvadaxistat did not achieve its primary ...