In this study, the investigators ablated liver cells in a mouse model, so they could assess liver cells or hepatocytes as ...

The accumulation of mutations in DNA is often mentioned as an explanation for the aging process, but it remains just one ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

A new process, nucleophagy, repairs damaged DNA that is particularly relevant for patients undergoing colorectal cancer ...

该研究表明，非编码DNA的损伤往往被隐藏了，它们在增殖缓慢的组织中积累得更多（例如肝脏或肾脏）。与频繁再生的器官不同，这些增殖缓慢的器官中的非编码DNA损伤长期未被发现，进而阻碍了细胞分裂。这些发现解释了什么有些器官（例如肝脏）比其他器官衰老得更快， ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

Careful replication and segregation of the DNA molecule, packaged into chromosomes, allows for the accurate inheritance of genetic instructions to each new daughter cell. DNA replication is a ...