▎药明康德内容团队编辑LENZTherapeutics今天宣布，美国FDA已接受其醋克立定（1.75% aceclidine）眼药水配方LNZ100用于治疗老花眼的新药申请（NDA）。根据之前所公布的3期试验结果，在不影响患者远视力（distance ...

Mid-stage presbyopia trials are also being run by Visus Therapeutics on Brimochol (carbachol and brimonidine tartrate) and LENZ Therapeutics on aceclidine. Novartis meanwhile is taking a different ...

Phentolamine acts as a pupil dilator. It's a similar approach to that taken by Visus Therapeutics with Brimochol – based on carbachol which acts like pilocarpine and brimonidine tartrate ...

Frontiers in Systems Neuroscience 8:145 [Abstract] [Content] Sparks DW, Chapman CA (2014) Contribution of Ih to the relative facilitation of synaptic responses induced by carbachol in the entorhinal ...

The FDSS/μCELL is a kinetic plate reader with an integrated dispensing head and imaging-based detector. Simultaneous dispensing into the entire 96/384-well plates and simultaneous detection of ...

Unlike other miotics such as pilocarpine and carbachol, aceclidine’s mechanism of action is pupil-selective, meaning it can activate the iris sphincter muscle and cause miosis of the pupil to a ...

Unlike other miotics such as pilocarpine and carbachol, aceclidine’s mechanism of action is pupil-selective, meaning it can activate the iris sphincter muscle and cause miosis of the ...