Research by the University of Plymouth showed spores of Clostridium difficile, commonly known as C. diff, are completely unaffected despite being treated with high concentrations of bleach used in ...

"C. diff can persist in multiple forms in the gut, including in biofilms and as an incredibly hardy spore, making it uniquely difficult to treat," said Joseph P. Zackular, PhD, co-director of the ...

Working with animals, Penn researchers modified the mRNA vaccine to target C. difficile, an infection that kills 30,000 in ...

Clostridioides difficile, a spore-forming and anaerobic gram-positive bacterium, causes a wide-spectrum diarrheal disease that can ultimately lead to life-threatening conditions such as toxic ...

C. difficile is a bacterium that can cause infection with symptoms ranging from diarrhea to deadly colon damage. It spreads quickly via its hard-to-kill spores and commonly infects vulnerable ...

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Clostridioides difficile is the most common cause of antibiotic-associated diarrhoea globally. Its spores have been implicated in the prevalence of C. difficile infection due to their resistance ...

Recurrent C. difficile infections also increase the risk of death by 33%. “Our product will be targeting the spores and live cells, neutralizing their activity and simultaneously targeting ...

The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection. "Where most vaccines are spurring one's ...

Our Clostridium botulinum research funded by several competitive grants from European and national sources and forms two major research lines: Fundamental research questions focus on environmental, ...

Disinfectant used in hospitals is no more effective than water at killing off a superbug, research suggests. According to the findings, one of the main chlorine disinfectants (bleach) used to ...

The data presented indicate a favorable gut bile acid profile which may contribute to ibezapostat's beneficial anti-recurrence effect in patients with C. difficile Infection (CDI) In the Phase 2b ...