Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis ...

A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...

K Heran Darwin is at New York University Grossman School of Medicine and a regular columnist for EMBO reports.

Human papillomavirus (HPV) and hyperactivated YAP1 form a YAP1-HPV oncogenic alliance to drive the malignant transformation ...

Changing nutrient environments challenge cells as they affect both protein biosynthesis and cell cycle length. This work ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...