Degradation of a Xenopus Kip1 orthologue, Xic1, is dependent on its recruitment to replication origins. This ensures that activation of Cdk2 and subsequent initiation of replication is co ...
We work in two areas. The first is traditional cell and molecular biology, focussed on the molecular mechanisms underlying mesoderm formation, and neural crest induction, and tissue and organ ...
I am interested in how these networks form. I am especially interested in the molecular pathways underlying this process. My lab studies these questions in the developing visual system of the Xenopus ...
So Ghent University molecular biologist Marjolein Carron and colleagues took a close look at the tropical clawed frog (Xenopus tropicalis) to see if our most distantly related nail-bearer could shed ...
This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...
We use techniques and models including optical mapping of ex vivo hearts, conventional and fluorescence-coupled electrophysiology (e.g. patch clamp, TEVC, voltage clamp fluorimetry, LRET), molecular ...