论文还展示了PURE平台的潜在临床应用场景。在体外三维培养的卵巢组织中，利用富含miR-130a的工程化EV激活卵泡mTOR信号通路，可显著提高原始卵泡体外激活。进一步将富含miR-130a的工程化EV的多孔水凝胶植入到衰老小鼠体内，可实现4周内EV ...

揭示细胞内精密的运输系统，我们可以将其类比为高效的城市物流网络。正如城市依赖精准的配送员确保包裹按时送达，细胞中的WDR11和TBC1D23负责识别特定信号，确保关键“包裹”——如蛋白质——精准运送至高尔基体这一“转运中心”。这些“配送员”不仅仅承担 ...

More information: Georgia K. Atkin-Smith et al, In situ visualization of endothelial cell-derived extracellular vesicle ...

From immunology to tumor biology, extracellular vesicle research is a growing field with diagnostic and therapeutic potential that researchers across life science disciplines can tap into with ...

Scientists are designing simplified biological systems, aiming to construct synthetic cells and better understand life’s ...

Exosomes are a type of extracellular vesicle. This is a scientific way of saying they are basically little packages that bud off from cells. They were once thought to contain cellular garbage, but now ...

Thousands of Serbian opposition backers rallied on Tuesday in the northwestern city of Nov Sad in a violent protest over a ...

A new study reveals a non-canonical cell signaling pathway orchestrated by a novel extraceullar vesicle. Proposed model for ARMMs-mediated non-canonical NOTCH2 signaling (1). Cells release important ...

His exploration of vesicle trafficking mechanisms in simple yeast cells has revealed the profound impact of evolution as a unifying principle, shedding light on the vast diversity of life on Earth ...

This is the first commercially available small particle detector on a cell sorter and offers a significant advancement for rapidly evolving research fields, including in drug delivery, cell therapy, ...