A small-molecule ligand that binds to a (CAG) n hairpin repeat is the basis of a biosensor to detect repeat length, which may help diagnose trinucleotide repeat disease severity. DNA trinucleotide ...

Huntington's disease is one of the devastating neurodegenerative disorders resulting from expansion of a genomic trinucleotide CAG repeat, which encodes a polyglutamine tract in causative proteins.

A total of 222 diarrheic calves (180 cattle and 42 buffaloes) were used in this study. The presence of the protozoan was ...

In the Carter-O'Connell lab we are focused on using biochemistry to uncover the role of ADP-ribosylation in both normal human physiology (cell development, signal transduction, gene regulation) and ...

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48. Arteaga, S. J., Dolenz, B. J., and Znosko, B. M. (2024) "Competitive influence of alkali metals in the ion atmosphere on nucleic acid duplex stability," ACS Omega ...