Reducing microglial activity in the presence of apolipoprotein E4 (APOE4) has uncovered a mechanism associated with the deposition of misfolded amyloid and tau in a novel mouse model of Alzheimer’s ...
We are interested in how novel non-neuronal mechanisms contribute to drug addiction. There is growing recognition that microglial proinflammatory actions play an important role in the brain’s response ...
The study by Power and colleagues is important as elucidating the dynamic immune responses to photoreceptor damage in vivo potentiates future work in the field to better understand the disease process ...