Low serum sodium concentrations in the blood are called hyponatremia, a prevalent clinical electrolyte disorder. In contrast ...

Chronic hyponatremia is a condition in which blood sodium levels are low, leading to neurological and mental problems.

Sugimura when asked the reason behind focusing on microglia for the study. Moreover, when these microglial cell lines were exposed to rapid correction of low sodium concentrations, the researchers ...

Microglia are the brain’s immune cells playing an important role in maintaining neural function and responding to potential ...

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

Dr Michael-John Dolan, a scientist at Trinity College Dublin. has won a highly prestigious European Research Council (ERC) ...

"We propose that two different types of microglial cells -- the immune cells of the brain -- begin the process of amyloid and tau accumulation that define Alzheimer's disease," De Jager says.

The scientist will focus on brain repair as a model system, with the ultimate goal of harnessing microglial states.

Perlmutter explained, “[i]t is now clear that metabolic dysfunction upstream of amyloid plaque formation is central to the activation of the brain’s microglial cells, and this phenotypic ...

However, when the brain is subjected to hyperosmotic stress—a condition characterized by elevated extracellular sodium levels, the microglial response can become exaggerated, leading to ...