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生物谷
13 天
Mol Cell:RNA Pol II和延伸因子的活细胞成像展示转录调控新机制
为了研究RNA Pol II 和转录因子结合的解离动力学,作者使用新型基因工程方法、成像工具和更为特异的抑制剂对果蝇多染色体进行了活细胞成像。 RNA聚合酶II (RNA Pol II) 介导的转录是一个高度调控的多步骤过程,负责产生所有mRNA,在不同的步骤中由蛋白质复合物 ...
The EMBO Journal
8 天
Multiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn’s ...
The gut microbiota and its functional metabolites play crucial roles in the development of intestinal fibrosis in patients ...
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