We suggest that future therapeutic strategies targeting the oncogenic network of CDK4/6, MEK, PD-L1, and FOXM1 represent ...
A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Linking FOXM1 and PD-L1 to CDK4/6 ...
耐药性能通过降低许多长期疗法的疗效,从而给很多乳腺癌患者带来了一大治疗难题,尽管一种特定的疗法能杀死大多数癌细胞,但仍然有很小一部分比例的癌细胞对疗法会产生一定的耐药性,并能使其存活、生长和扩散。癌细胞的生存和生长的能力依赖于细胞增殖和细胞死亡之间的 ...
A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, “Linking FOXM1 and PD-L1 to CDK4/6 ...
本文研究结果表明,揭示能克服药物耐受性的活性和细胞死亡通路的改变,或许能帮助确定可能能最好地预防或逆转对FOXM1治疗靶向性耐药的手段 ...
An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for ...
美国弗吉尼亚大学医学院李辉实验室一直从事融合基因领域研究,在融合基因领域有很多重大发现。儿童癌症中的基因融合被列为“癌症登月计划”的十大重点领域之一,指出了基因融合的重要性以及迫切需要推进儿童癌症治疗。 【详细全文】 胶质母细胞瘤 ...
The transcription factor protein FoxM1, a key regulator of the cell division cycle, is inappropriately activated in cancer. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of ...
Good news!A 30-year-old woman missing from the Westmead area has been located safe.Police would like to thank the public and media for their ...