A complex system, such as a cluster of many atoms or a biomolecule, behaves differently: The atoms can often arrange themselves into different conformations, which often have very similar energies.
There is a change in the conformation (or shape) of PrP in the abnormal form, and there seem to be some differences in the conformations found between some TSE strains. Perhaps abnormal PrP can ...
the Spike protein in both its open and closed conformations as well as Ab94 are shown. The most important factor in our typical search for monoclonal antibody treatments is their neutralizing ...