Neuroligin 3是神经核团之间突触连接重要的黏附分子，家系遗传研究中发现其编码基因 Nlgn3 中的R451C变异与自闭症密切关联。本文研究团队提出自闭症相关基因 Nlgn3 ...

Eukaryotic cells – that is, cells with a nucleus – possess an astounding ability to radically change their shape and their cytoskeleton, allowing them to migrate through tiny pores and constrictions ...

Human cell nuclei with fluorescently labeled chromatin (green) and nucleoli (red). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

Research led by LMU's Joachim Rädler uncovers how cancer cell nuclei deform when migrating through narrow channels. Using synthetic microstructures and advanced microscopy, the study shows that ...

An analysis of tissue samples from nearly 1,200 older adults found that the more insertions individuals had, the younger they died.

因此，尽管体外的脑区间连接模型缺乏体内发育过程中众多参与因素，但这却为他们探索在不同人脑区域之间如何建立靶向性投射连接的调控机制提供了一个清晰、简便的背景，并能打造出来人源性的研究模型。

In this way, the researchers investigated the mechanics and dynamics of cancer cell nuclei that migrated through deformable 3D hydrogel channels. "Using confocal imaging and hydrogel bead ...

Together, the findings suggested that 17α-estradiol extensively reshaped the cell populations, cellular communication, neuropeptide secretion, and neural synapse activity in aged hypothalamus, which ...