which is caused by the fatal tropical disease Trypanosoma brucei rhodesiense. PaxMedica plans to file a new drug application for PAX-101 in Q4. The company also hopes to advance the product into ...

Figure 1 shows energy metabolism in Trypanosoma brucei, the parasite responsible for African sleeping sickness. On the surface, the scheme appears of little use in suggesting likely targets for ...

The first movie (on the left) shows serial tilted views of the 120 nm thick section from a cell of Trypanosoma brucei . Images were collected (TEM Tecnai F20) at one degree intervals over a range from ...

Botana, A.; Eurtivong, C.; Bhambra, Avninder S. dc.description.abstract: Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense ...

The nuclear pore complex (NPC) mediates transport of all macromolecules between the nucleus and the cytoplasm. The structure of the NPC — a cylindrical ring-like structure lined with ...

Effective substances successfully extracted from herbs We have found several herb extracts that are useful in HIV infection control, and have also pinned down active components capable of suppressing ...

Parasitology research includes the biology, epidemiology and control of parasitic diseases of farmed livestock, companion animals and wildlife, both in the UK and internationally. The wide range of ...

Identification of potent COVID-19 main protease inhibitors by loading of favipiravir on Mg12O12 and Zn12O12 nanoclusters: an in silico strategy for COVID-19 treatment.