2 [Alt text] From left to right, the figure outlines key elements of posttranscriptional pre-mRNA splicing: an RNA transcript (pre-mRNA) displaying introns and exons, and six common splicing ...

The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript ...

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript ...

However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...

Using NGS in prognostic assessments enhances myelofibrosis prognosis and survival estimates, representing a step toward personalized medicine in myelofibrosis.

Macrophages are important cellular reservoirs of chikungunya virus (CHIKV), but the viral and host determinants that ...