This pattern reflects the deep penetration of the Sertoli cells by the spermatid bundles. As spermatogenesis progresses, the bundling of the elongating spermatids stops, coincident with the ...

In normal testicular tissue, and in tissue in the proximity of a testicular tumor, the myoid cells and endothelial cells strongly expressed P-gp and BCRP; the Sertoli cells expressed MRP1 ...

Nonobstructive azoospermia (NOA) affects 5%–15% of men undergoing infertility evaluation, accounting for nearly 60% of ...

due to the tight junctions of Sertoli and epithelial cells. [36] This creates favorable conditions for spermatogenesis and sperm survival in the testicular fluid, and sperm maturation in the ...

Cancer of the testes (testicles) involving the Sertoli or Leydig cells has also been reported in men. Screening guidelines may change over time as new technologies are developed and more is learned ...

The identification of functionally relevant ASA antigens is a prerequisite for treatment options. Currently, no antibody-specific treatment of autoimmune diseases is possible, but the treatment is ...