Recent advances in the study of proteomes (i.e., the entire range of proteins expressed by human cells and tissues) have opened new opportunities for identifying the biological markers of specific ...

metagenomes and proteomes. This allows us to uncover new antibiotics at digital speed." Given that bacteria evolve quickly, ...

residues in aging proteomes. Specifically, the formation of trioxidized Cys (t-Cys) results in permanent protein damage. Recent findings in rodents have revealed that irregular regulation of t-Cys ...

Anita Saraf investigates mosquito saliva to understand how viruses like dengue and West Nile are transmitted, using mass ...

Now that researchers have identified whole complements of proteins (proteomes) for many cell types, they are pushing the frontiers of protein science: from the regulation and function of single ...

Scientists’ goal is not to resurrect vanished creatures but discover whether ancient molecules can solve modern problems ...

Currently, our work is focused on refractory leukemias and solid tumors. We are interested in understanding the principles by which the genomes and proteomes of these tumors are disorganized, and in ...

A surgeon makes small incisions in the eye, sucks out the cloudy lens and replaces it with an artificial lens implant.

With a new two-year grant of $250,000 per year from the U.S. Department of Agriculture’s National Bio and Agro-Defense ...

A study published June 26 in Science Translational Medicine adds to the growing pile of proteomics data implicating cellular processes such as autophagy, ubiquitination, endocytosis, and glycolysis as ...

Indeed, metazoan proteomes have no discernable homologs of the sealing domain of fungal/plant tRNA ligase. Metazoa rely for end-joining during tRNA splicing and the unfolded protein response on RtcB ...

Stephen Elledge and colleagues have developed a new technology to analyse global protein stability (GPS) in live cells, in real time and with single-cell resolution. The fluorescence-based system ...