研究团队发现内脏和躯体疼痛分别激活下丘脑室旁核(paraventricular hypothalamus,PVH)中转录组特征显著不同的两群神经元,其中内脏疼痛激活的神经元特异性高表达P2X嘌呤能受体3(P2X Purinergic Receptor 3,P2X3R),而躯体疼痛激活的神经元则特异性高表达血管活性肠 ...
The protein they studied is the P2X 7 receptor, an ion channel that is found throughout the body. P2X 7 is unique: once it's ...